Mouse Ttr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttr
Locus ID	22139
Kit Components	GA204486G1, Ttr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204486G2, Ttr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204486G3, Ttr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013697
Synonyms	AA408768; AI787086; D17860; prealbumin
Summary	This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease. [provided by RefSeq, Mar 2010]

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