Mouse Wars activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wars
Locus ID	22375
Kit Components	GA204616G1, Wars gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204616G2, Wars gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204616G3, Wars gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164314, NM_001164488, NM_011710
Synonyms	TrpRS; WRS
Summary	T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (By similarity).[UniProtKB/Swiss-Prot Function]

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