Mouse Ncdn activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ncdn
Locus ID	26562
Kit Components	GA205003G1, Ncdn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205003G2, Ncdn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205003G3, Ncdn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011986, NM_001355412, NM_001355413
Synonyms	AU042419; mKIAA0607; MMS10-AE; Ms10ae; norbin
Summary	Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.[UniProtKB/Swiss-Prot Function]

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