Mouse Dkkl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dkkl1
Locus ID	50722
Kit Components	GA205337G1, Dkkl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205337G2, Dkkl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205337G3, Dkkl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015789
Synonyms	AI414495; mSgy; SGY; SGY-1; SGY1; Soggy
Summary	Involved in fertilization by facilitating sperm penetration of the zona pellucida (PubMed:19596312, PubMed:22817830). May promotes spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduces testosterone synthesis in Leydig cells (PubMed:18818293). Is not essential either for development or fertility (PubMed:19596310).[UniProtKB/Swiss-Prot Function]

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