Mouse Epb41l4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Epb41l4b
Locus ID	54357
Kit Components	GA205679G1, Epb41l4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205679G2, Epb41l4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205679G3, Epb41l4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019427, NM_001355492
Synonyms	6430543G08Rik; AA589614; AU021054; BB007528; D4Ertd346e; Ehm2; Epb4.1l4b; Lulu2
Summary	Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (PubMed:22006950). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (By similarity). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (By similarity).[UniProtKB/Swiss-Prot Function]

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