Mouse Setd6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Setd6
Locus ID	66083
Kit Components	GA206564G1, Setd6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206564G2, Setd6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206564G3, Setd6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001035123, NM_001368354
Synonyms	0610039J04Rik; 3110004G14Rik; AI413388; C76402
Summary	Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity). Required for the maintenance of embryonic stem cell self-renewal (PubMed:23324626).[UniProtKB/Swiss-Prot Function]

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