Mouse Apoa5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Apoa5
Locus ID	66113
Kit Components	GA206582G1, Apoa5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206582G2, Apoa5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206582G3, Apoa5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_080434, NM_001348095
Synonyms	1300007O05Rik; Apoav; RAP3
Summary	Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity).[UniProtKB/Swiss-Prot Function]

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