Mouse Atp6v1g1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atp6v1g1
Locus ID	66290
Kit Components	GA206690G1, Atp6v1g1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206690G2, Atp6v1g1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206690G3, Atp6v1g1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024173
Synonyms	1810024D14Rik; AA960677; Atp6g1; ATP6J; VAG1; Vma10
Summary	Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function]

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