Mouse Jagn1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Jagn1
Locus ID	67767
Kit Components	GA207504G1, Jagn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207504G2, Jagn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207504G3, Jagn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001205025, NM_001243739, NM_026365, NR_037974
Synonyms	5830427H10Rik
Summary	Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.[UniProtKB/Swiss-Prot Function]

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