Mouse Zdhhc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zdhhc3
Locus ID	69035
Kit Components	GA208026G1, Zdhhc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208026G2, Zdhhc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208026G3, Zdhhc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026917
Synonyms	1110020O22Rik; 1810006O10Rik; 2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373
Summary	Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability (PubMed:15229235). Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (PubMed:16129400). May also palmitoylate DLG4, DNAJC5 and SNAP25 (PubMed:15603741, PubMed:25253725).[UniProtKB/Swiss-Prot Function]

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