Mouse Sec62 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sec62
Locus ID	69276
Kit Components	GA208113G1, Sec62 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208113G2, Sec62 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208113G3, Sec62 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027016, NM_001357528
Synonyms	3100002M17Rik; AI844545; AW545092; Dtrp1; HTP1; Tloc1
Summary	Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.[UniProtKB/Swiss-Prot Function]

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