Mouse Tmprss6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmprss6
Locus ID	71753
Kit Components	GA208926G1, Tmprss6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208926G2, Tmprss6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208926G3, Tmprss6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027902, NM_001355601
Synonyms	1300008A22Rik
Summary	Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HJV, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.[UniProtKB/Swiss-Prot Function]

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