Mouse Pdia6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdia6
Locus ID	71853
Kit Components	GA208978G1, Pdia6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208978G2, Pdia6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208978G3, Pdia6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027959
Synonyms	1700015E05Rik; AL023058; C77895; CaBP5; P5; Txndc7
Summary	May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:24508390). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (By similarity). May also regulate the UPR via the EIF2AK3 UPR sensor (By similarity). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (By similarity).[UniProtKB/Swiss-Prot Function]

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