Mouse Uaca activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Uaca
Locus ID	72565
Kit Components	GA209276G1, Uaca gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209276G2, Uaca gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209276G3, Uaca gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028283, NM_001357407, NM_001357408
Synonyms	2700059D02Rik; nucling
Summary	Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.[UniProtKB/Swiss-Prot Function]

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