Mouse Rftn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rftn2
Locus ID	74013
Kit Components	GA209673G1, Rftn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209673G2, Rftn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209673G3, Rftn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028713, NM_001356287, NM_001356288
Synonyms	2700010E02Rik; 3222401M22Rik
Summary	Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195). May regulate B-cell antigen receptor-mediated signaling.[UniProtKB/Swiss-Prot Function]

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