Mouse Kntc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kntc1
Locus ID	208628
Kit Components	GA212877G1, Kntc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212877G2, Kntc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212877G3, Kntc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042421
Synonyms	D330012D13; jgl
Summary	Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (By similarity).[UniProtKB/Swiss-Prot Function]

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