Mouse Afg1l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Afg1l
Locus ID	215951
Kit Components	GA213310G1, Afg1l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213310G2, Afg1l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213310G3, Afg1l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145743, NM_001359297
Synonyms	CG8520
Summary	Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain. Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress.[UniProtKB/Swiss-Prot Function]

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