Mouse Btf3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Btf3
Locus ID	218490
Kit Components	GA213550G1, Btf3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213550G2, Btf3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213550G3, Btf3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001170540, NM_145455
Synonyms	1700054E11Rik
Summary	When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription (By similarity).[UniProtKB/Swiss-Prot Function]

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