Mouse Smg7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Smg7
Locus ID	226517
Kit Components	GA213865G1, Smg7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213865G2, Smg7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213865G3, Smg7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001005507, NM_001160256, NM_001160257, NM_001359257
Synonyms	9430023P16Rik; mKIAA0250
Summary	Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation (By similarity).[UniProtKB/Swiss-Prot Function]

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