Mouse Eif5b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eif5b
Locus ID	226982
Kit Components	GA213903G1, Eif5b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213903G2, Eif5b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213903G3, Eif5b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_198303
Synonyms	A030003E17Rik; BC018347; IF2
Summary	Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.[UniProtKB/Swiss-Prot Function]

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