Mouse Sorbs2 activation kit by CRISPRa

CAT#: GA214514

Sorbs2 CRISPRa kit - CRISPR gene activation of mouse sorbin and SH3 domain containing 2



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Sorbs2
Locus ID 234214
Kit Components

GA214514G1, Sorbs2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214514G2, Sorbs2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214514G3, Sorbs2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001205219, NM_001310707, NM_001310708, NM_172752
Synonyms 2010203O03Rik; 9430041O17Rik; A530071H08; Argbp2; mKIAA0777; nArgBP2
Summary Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 (By similarity). May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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