Mouse Awat2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Awat2
Locus ID	245532
Kit Components	GA215276G1, Awat2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215276G2, Awat2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215276G3, Awat2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290395, NM_177746
Synonyms	9430062J17Rik; ARAT; Dgat2l4; WS
Summary	Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo (By similarity).[UniProtKB/Swiss-Prot Function]

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