Mouse Iqcb1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Iqcb1
Locus ID	320299
Kit Components	GA216467G1, Iqcb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216467G2, Iqcb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216467G3, Iqcb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177128
Synonyms	6820449I09Rik; AV128382; NPHP5
Summary	Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6 (By similarity). Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6 (By similarity).[UniProtKB/Swiss-Prot Function]

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