Mouse Slc7a6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc7a6
Locus ID	330836
Kit Components	GA216853G1, Slc7a6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216853G2, Slc7a6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216853G3, Slc7a6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178798, NM_001357381, NM_001357382, NR_151676, NR_151677
Synonyms	AI643885; LAT-2; LAT3
Summary	Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial cells (By similarity).[UniProtKB/Swiss-Prot Function]

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