GADD34 (PPP1R15A) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	GADD34
Locus ID	23645
Kit Components	KN200581G1, GADD34 gRNA vector 1 in pCas-Guide CRISPR vector KN200581G2, GADD34 gRNA vector 2 in pCas-Guide CRISPR vector KN200581BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Reference Data
RefSeq	NM_014330
Synonyms	GADD34
Summary	This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]

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