Rccd1 (NM_173445) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR205878 protein sequence Red=Cloning site Green=Tags(s) MAEKRHGAWFGFGFCGFGQALGSGNSHHSVYSPEPLHASDDICQVSAGWSYTALVTRGGRVELSGSVSGA ADGCRDVWASEELLVLLRNKGGASTELQAWVPGSALQGEPLWVQNLVSGAKGQGEDEPSRESRMGTLPLL PCARAYVTPEPPFCQPLAPELRVRQLELGAEHVLLLCTAGQVFSWGAGRHGQLGHGTLEAELEPRLLEAL QGLRMAKVAAGGWHSVCLSETGDIYIWGWNESGQLALPTRSGTEKKAEREEATELNEDGLKEELAVADAG APAHFIAIQPFPALLDLPLGSDAVMASCGSRHTAVVTRTGELYTWGWGKYGQLGHKDSTSLDRPCCVEYF VERQLEVRAVTCGPWNTYVYAMERDKS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	40.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_775621
Locus ID	269955
UniProt ID	Q8BTU7
Refseq Size	2340
Cytogenetics	7 D2
Refseq ORF	1131
Synonyms	5830436H09; E430018M08Rik
Summary	Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.[UniProtKB/Swiss-Prot Function]

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