Sycp3 (NM_011517) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR225489 protein sequence Red=Cloning site Green=Tags(s) MLRGCGDSDSSPEPLSKHLKMVPGGRKHSGKSGKPPLVDQPKKAFDFEKDDKDLSGSEEDVADEKAPVID KHGKKRSAGIIEDVGGEVQNMLEKFGADINKALLAKRKRIEMYTKASFKASNQKIEQIWKTQQEEIQKLN NEYSQQFMNVLQQWELDIQKFEEQGEKLSNLFRQQQKIFQQSRIVQSQRMKAIKQIHEQFIKSLEDVEKN NDNLFTGTQSELKKEMAMLQKKVMMETQQQEMANVRKSLQSMLF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	29.3 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_035647
Locus ID	20962
UniProt ID	P70281
Refseq Size	1132
Cytogenetics	10 C1
Refseq ORF	762
Synonyms	Cor1; Scp3
Summary	Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:11311943, PubMed:22761579). Required for centromere pairing during meiosis in male germ cells (PubMed:22761579). Required for normal meiosis during spermatogenesis and male fertility (PubMed:10678170). Plays a lesser role in female fertility (PubMed:10678170, PubMed:12004129). Required for efficient phosphorylation of HORMAD1 and HORMAD2 (PubMed:22346761).[UniProtKB/Swiss-Prot Function]

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