Haptoglobin (HP) (NM_005143) Human Recombinant Protein

CAT#: TP721131L

Purified recombinant protein of Human haptoglobin (HP), transcript variant 1

Size: 10 ug 500 ug 1 mg



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CNY 18,030.00


货期*
2周

规格
    • 500 ug

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经常一起买 (1)
Anti-HP mouse monoclonal antibody, clone OTI4H5 (formerly 4H5)
    • 100 ul

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Val19-Gln160(alpha chain)&Ile162-Asn406(beta chain)
Tag C-His
Predicted MW 44.4 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS,PH7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq NP_005134
Locus ID 3240
UniProt ID P00738, Q6PEJ8
Refseq Size 1433
Cytogenetics 16q22.2
Refseq ORF 1218
Synonyms BP; HP2ALPHA2; HPA1S
Summary This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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