Tfam Mouse Recombinant Protein
CAT#: TP724627
Recombinant Mouse Transcription factor A, mitochondrial/mTFAM (N-His)
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CNY 2,380.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Mouse |
Protein Source | E. coli |
Expression cDNA Clone or AA Sequence |
S43-H243
|
Tag | N-6His |
Buffer | Supplied as a 0.2 um filtered solution of 5umM TES, pH7.5 |
Note | Recombinant mouse mTFAM is produced by E.coli. The target gene encoding S43-H243 is expressed with a 6His tag at the N terminus. |
Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 21780 |
UniProt ID | P40630 |
Summary | Mitochondrial transcription factor A (TFAM) is a double box high-mobility group DNA-binding and bending protein. The mitochondrial isoform of TFAM is widely expressed, whereas the nuclear isoform is testis-specific. TFAM plays an essential role in the activation of mitochondrial transcription and mitochondrial genome replication. It facilitates the transcription of the mitochondrial genome by binding mitochondrial promoter DNA. Studies in mice found that TFAM play a central role for embryonic development and is required to maintain the normal levels of mitochondrial genome copy. |
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