Perforin (PRF1) Mouse Monoclonal Antibody [Clone ID: dG9]

Specifications

Product Data
Clone Name	dG9
Applications	FC
Recommend Dilution	Flow cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Bovine, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified granules from human YT lymphoma cell line
Specificity	This antibody recognizes perforin, a 70 kDa protein expressed in cytoplasmic granules of cytotoxic T cells and NK cells.
Formulation	Phosphate buffered saline (PBS) Label: PE State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	perforin 1
Database Link	Entrez Gene 5551 Human UniProt ID P14222
Background	Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
Synonyms	Perforin-1, Pore forming protein, PFN, PFP, Cytolysin
Reference Data

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