Hepatitis B Surface Antigen / HBsAg (ay) Mouse Monoclonal Antibody [Clone ID: 057-17004]

Specifications

Product Data
Clone Name	057-17004
Applications	ELISA
Recommend Dilution	ELISA: Use this antibody as Detection and AM00876PU-N as Capture antibody.
Reactivity	Hepatitis B Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified HBsAg subtypes ad and ay
Specificity	This antibody reacts to Hepatitis B Surface Antigen (HBsAg) ay subtype.
Isotype	IgG2a
Formulation	10mM Phosphate, pH 7.4 containing 150mM Sodium Chloride and 0.05% Sodium Azide State: Purified State: Liquid (0.2µm filtered) purified IgG fraction (>90% pure by SDS-PAGE).
Concentration	lot specific
Purification	Protein A Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one week or (in aliquots) at -40°C for longer. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Synonyms	HBV surface antigen, Hepatitis B Virus
Reference Data

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