TNFRSF4 Mouse Monoclonal Antibody [Clone ID: 7D6]

Specifications

Product Data
Clone Name	7D6
Applications	FC, WB
Recommend Dilution	Flow Cytometry: 1/5; use 10µl of the suggested working dilution to label 1x10e6 cells in 100µl.
Reactivity	Feline, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CHO-derived feline CD134-Fc fusion protein.
Specificity	This antibody recognizes Feline CD134, otherwise known as OX40. The antibody weakly reacts with Human. It does not react with Mouse.
Isotype	IgG1
Formulation	Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide, 1% BSA Label: FITC State: Liquid purified Ig fraction Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chomatography on Protein G
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor receptor superfamily member 4
Database Link	Entrez Gene 7293 Human UniProt ID P43489
Background	CD134 is a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.
Synonyms	TNFRSF4, TXGP1L, ACT35 antigen, OX40L receptor
Reference Data

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