Canine Heartworm Mouse Monoclonal Antibody [Clone ID: HW1-39]

Specifications

Product Data
Clone Name	HW1-39
Applications	ELISA, WB
Recommend Dilution	ELISA: May be used in an indirect ELISA or as a capture antibody in a sandwich ELISA with AM01142BT-N. Western Blot: detects band/s of approximately 170, 155, 98, 80, 70 and 62kDa under reducing conditions.
Reactivity	Canine
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes both male and female ether extracted parasite antigen of Canine Heartworm.
Isotype	IgG1
Formulation	PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Canine heartworm infection, caused by the filarial nematode Dirofilaria immitis, is an insidious and potentially fatal condition transmitted by mosquitoes, which primarily affects the heart and lungs of dogs, but may also affect other species including cats, foxes, sea-lions, ferrets and humans. Canine heartworm disease, resulting ultimately in damage to the pulmonary vasculature system, is largely attributed to the immunological response of the host to the presence of the adult parasites, and in many cases their microscopic offspring (microfilaria) which circulate in the bloodstream, but growing evidence suggests the involvement of further factors/mediators.
Synonyms	Dirofilaria immitis
Reference Data

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