ZAP70 Mouse Monoclonal Antibody [Clone ID: SBZAP]

Specifications

Product Data
Clone Name	SBZAP
Recommend Dilution	Flow Cytometry: Membrane permeabilisation is required.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH.
Specificity	This antibody recognises human ZAP-70.
Isotype	IgG1
Formulation	PBS Label: FITC State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Gene Name	zeta chain of T cell receptor associated protein kinase 70kDa
Database Link	Entrez Gene 7535 Human UniProt ID P43403
Background	ZAP-70 is a 70kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.
Synonyms	ZAP-70, ZAP 70, SRK
Reference Data

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