TLR2 Mouse Monoclonal Antibody [Clone ID: 11G7]

Specifications

Product Data
Clone Name	11G7
Applications	FC
Recommend Dilution	Immunoprecipitation. Flow Cytometry: Use 10 µl of the suggested working dilution to label 1x106 cells in 100 µl. (1/100-1/200).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises the Toll-like receptor 2 (TLR2). Antibody 11G7 has been reported to block IL-6 cytokine production in response to ara-lipoarabinomannan (araLAM) and tripalmitoyl cysteinyl lipopeptide (Pam3CSK4) (1). 11G7 does not inhibit the production of cytokines induced by zymosan stimulation.
Isotype	IgG1
Formulation	PBS, pH 7.4 Label: PE State: Lyophilized purified IgG fraction from tissue culture supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore in 1 ml disilled water
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	PE
Storage Condition	Prior to and following reconstitution store undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	toll like receptor 2
Database Link	Entrez Gene 7097 Human UniProt ID O60603
Background	TLR2 is a 90kD type 1 transmembrane protein that is primarily expressed by peripheral blood monocytes. TLR2, also known as CD282, is reported to respond to a diverse range of bacterial cell wall components, mediating the innate immune response in co-operation with MD-2.
Synonyms	Toll-like receptor 2
Reference Data

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