Laminin 5 (LAMB3) Mouse Monoclonal Antibody [Clone ID: 6F12]

Specifications

Product Data
Clone Name	6F12
Applications	ELISA, IHC, WB
Recommend Dilution	Western blot (See Ref.1)  ELISA: This antibody is used as Coating antibody in Sandwich ELISA (See Ref.3,5)  Immunohistochemistry on Cryo Sections (See Ref.2,4,6)
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Laminin 5 beta 3 chain
Specificity	This antibody detects Laminin 5.
Isotype	IgG
Formulation	PBS, pH 7.4 State: Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore in 100 µl aqua bidest
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	laminin subunit beta 3
Database Link	Entrez Gene 3914 Human UniProt ID Q13751
Background	Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms	LAMB3, LAMNB1, Laminin subunit beta-3, Laminin 5, Laminin B1k chain, Kalinin B1 chain
Reference Data

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