Cyclophilin B (PPIB) (26-216) Mouse Monoclonal Antibody [Clone ID: k2E2]

Specifications

Product Data
Clone Name	k2E2
Applications	ELISA, FACS, ICC/IF, WB
Recommend Dilution	ELISA. Western blot: 1/1,000-1/2,000 (recommended starting dilution is 1/1,000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human Cyclophilin B (26-216aa) purified from E. coli
Specificity	This antibody detects Cyclophilin B.
Isotype	IgG1, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	peptidylprolyl isomerase B
Database Link	NP_000933 Entrez Gene 5479 Human UniProt ID P23284
Background	Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Cyclophilin B is necessary for the prolactin-induced proliferation, cell growth, and the nuclear retrotransport of prolactin.
Synonyms	Peptidyl-prolyl cis-trans isomerase B, Peptidylprolyl isomerase B, PPIase B, Cphn-2, Cyclophilin B, CYP-20b, CYPB, CYP-S1, OI9, Rotamase B, S-cyclophilin, SCYLP
Reference Data

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