Hsp105 (HSPH1) (Isoform alpha) Mouse Monoclonal Antibody [Clone ID: J1G12]

Specifications

Product Data
Clone Name	J1G12
Applications	ELISA, FACS, ICC/IF, WB
Recommend Dilution	ELISA. Western blot: 1:500 ~ 1,000 (starting dilution 1:1000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human Hsp105 alpha (1-858aa) purified from E. coli
Specificity	This antibody detects Heat Shock Protein 105 alpha (HSP105a).
Isotype	IgG2b, kappa
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Concentration	1mg/ml (determined by BCA assay)
Purification	By protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Gene Name	heat shock protein family H (Hsp110) member 1
Database Link	NP_006635 Entrez Gene 10808 Human UniProt ID Q92598
Background	Hsp105 is a mammalian member of the HSP105/110 family, a diverged subgroup of the HSP70 family. HSP105 exists as two isoforms, alpha and beta. Hsp105 alpha associates with Hsp70/Hsc70 as complexes in vivo and regulates the chaperone activity of Hsp70/Hsc70 negatively in vitro and in vivo. Hsp105 alpha is constitutively expressed and also induced by various stress, whereas Hsp105beta, lacking 44 amino acids from Hsp105 alpha, is specifically expressed during mild heat shock. Although Hsp105 alpha is shown to localize in the cytoplasm of mammalian cells, cellular localization of Hsp105beta is not known.
Synonyms	Heat shock 105kDa/110kDa protein 1, HSPH1, Heat shock 105kDa/110kDa protein 1, HSP105alpha, HSP105-alpha, Heat shock 105kDa/110kDa protein 1 Antigen NY CO 25, DKFZp686M05240, Heat shock 105kD, Heat shock 105kD alpha, Heat shock 105kD beta, Heat shock 105kDa protein, Heat shock 105kDa protein 1, Heat shock 110kDa protein, Heat shock protein 105 kDa, HSP105A, HSP105B, HSP110, HSPH 1, KIAA0201, NY CO 25
Reference Data

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