CD94 (KLRD1) Mouse Monoclonal Antibody [Clone ID: DX22]

Specifications

Product Data
Clone Name	DX22
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/50-1/100 diluted antibody to label 1 x 10e6 cells in 100 µl.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Natural killer cell line. Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0 myeloma cell line.
Specificity	This antibody is specific for CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). Clone DX22 is reported to inhibit the binding of CD94 to HLA-E(2) and HLA-G(4). We recommend the use of AM05552AF-N for functional studies.
Isotype	IgG1
Formulation	Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	killer cell lectin like receptor D1
Database Link	Entrez Gene 3824 Human UniProt ID Q13241
Background	CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes. CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes.
Synonyms	KLRD1, KP43, NK cell receptor
Reference Data

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