Ltbr Rat Monoclonal Antibody [Clone ID: 5G11b]

CAT#: AM05877PU-N

Ltbr rat monoclonal antibody, clone 5G11b, Purified



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CNY 5,434.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 5G11b
Applications FC
Recommend Dilution Flow cytometry: use 10 µl of 1/50 - 1/100 dilution to label 10e6 cells in 100 µl.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Recombinant extracellular domain of LT beta R
Specificity This antibody recognises lymphotoxin-beta receptor (LT beta R), a member of the tumour necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognises surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (2).
This product is routinely tested on WEH1 cells.
Formulation Phosphate buffered saline pH7.4, 0.09% Sodium Azide
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name lymphotoxin B receptor
Background The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
Synonyms Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR, TNFRSF3, D12S370, Lymphotoxin-beta receptor
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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