ITGAL Mouse Monoclonal Antibody [Clone ID: BL1H8]

Specifications

Product Data
Clone Name	BL1H8
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl. Functional Assays: Removal of Sodium Azide is recommended prior to use.
Reactivity	Bovine, Porcine, Sheep
Host	Mouse
Clonality	Monoclonal
Immunogen	Porcine alveolar macrophages.
Specificity	This antibody is specific for the porcine CD11a cell surface antigen, which is expressed on a range of cells including peripheral blood mononuclear cells, monocytes, granulocytes and alveolar macrophages. Clone BL1H8 is reported to inhibit Con-A driven T-cell proliferation and the mixed lymphocyte reaction (1).
Isotype	IgG2b
Formulation	Phosphate buffered saline pH 7.4, 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Database Link	Entrez Gene 281874 Bovine UniProt ID P61625
Background	CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.
Synonyms	Integrin alpha-L, LFA1, LFA-1
Reference Data

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