SLA CLASS II DR Mouse Monoclonal Antibody [Clone ID: 2E9/13]

Specifications

Product Data
Clone Name	2E9/13
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry: Use 10 μl of 1/25-1/200 diluted antibody to label 106 cells in 100 μl. Immunoprecipitation: This antibody immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled porcine peripheral blood mononuclear cells. Immunohistochemistry on Frozen Sections.
Reactivity	Bovine, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Porcine monocytes.
Specificity	Clone 2E9/13 is specific for SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells. This clone reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognises a monomorphic determinant of porcine SLA DR. Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B, see Bullido, R. et al. for details.
Isotype	IgG2b
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR.
Synonyms	MHC Class II DR
Reference Data

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