Visfatin (NAMPT) Mouse Monoclonal Antibody [Clone ID: 1D3A12]

Specifications

Product Data
Clone Name	1D3A12
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000.  Western Blotting: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.
Specificity	Recognizes PBEF1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	nicotinamide phosphoribosyltransferase
Database Link	Entrez Gene 10135 Human UniProt ID P43490
Background	PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Synonyms	NAmPRTase, PBEF, PBEF1
Reference Data

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