Eph receptor B2 (EPHB2) Mouse Monoclonal Antibody [Clone ID: 2D12C6]

Specifications

Product Data
Clone Name	2D12C6
Applications	ELISA, IF, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of EphB2 (aa17-200) expressed in E. Coli.
Specificity	Recognizes EPH receptor B2 (EphB2).
Isotype	IgG2b
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	EPH receptor B2
Database Link	Entrez Gene 2048 Human UniProt ID P29323
Background	Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Synonyms	Ephrin type-B receptor 2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5, NY-REN-47
Reference Data

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