PARL Mouse Monoclonal Antibody [Clone ID: 8C4B2]

Specifications

Product Data
Clone Name	8C4B2
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
Specificity	Recognizes PARL (presenilin associated, rhomboid-like).
Isotype	IgG2b
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	presenilin associated rhomboid like
Database Link	Entrez Gene 55486 Human UniProt ID Q9H300
Background	This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	PSARL, PRO2207
Reference Data

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