Lipoprotein a (LPA) Mouse Monoclonal Antibody [Clone ID: 8F6A9]

Specifications

Product Data
Clone Name	8F6A9
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of LPA (1823-2013 aa) expressed in E. Coli
Specificity	Recognizes LPA, Lipoprotein, Lp(a)
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lipoprotein(a)
Database Link	Entrez Gene 4018 Human UniProt ID P08519
Background	Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/gp 330. Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation.
Synonyms	Apo(a), LPA
Reference Data

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