FMRP (FMR1) Mouse Monoclonal Antibody [Clone ID: 4G9]

Specifications

Product Data
Clone Name	4G9
Applications	IF, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human FMR1 expressed in E. Coli.
Specificity	Recognizes FMR1 also known as POF, FMRP, FRAXA.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	71 kDa
Gene Name	fragile X mental retardation 1
Database Link	Entrez Gene 2332 Human UniProt ID Q06787
Background	FMR1, also known as POF, FMRP, FRAXA. Entrez Protein is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.
Synonyms	Fragile X mental retardation 1 protein, Protein FMR-1
Reference Data

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