MATK Mouse Monoclonal Antibody [Clone ID: 9D7]

Specifications

Product Data
Clone Name	9D7
Applications	ELISA, FC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human MATK expressed in E. Coli.
Specificity	This antibody reacts to MATK.
Isotype	IgG1
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 50% glycerol Preservative: 0,03'% sodium azide
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	56 kDa
Gene Name	megakaryocyte-associated tyrosine kinase
Database Link	Entrez Gene 4145 Human UniProt ID P42679
Background	MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Synonyms	Megakaryocyte-associated tyrosine-protein kinase, CHK, CTK, HYL, HYLTK
Reference Data

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