DKK3 Mouse Monoclonal Antibody [Clone ID: 4G7]

Specifications

Product Data
Clone Name	4G7
Applications	ELISA, FC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human DKK3 expressed in E. Coli.
Specificity	Recognizes Dkk-3 (Dickkopf-3).
Isotype	IgG1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	38 kDa
Gene Name	dickkopf WNT signaling pathway inhibitor 3
Database Link	Entrez Gene 27122 Human UniProt ID Q9UBP4
Background	Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-richdomains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
Synonyms	Dickkopf-related protein 3, Dkk-3, REIC
Reference Data

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