STAT6 Mouse Monoclonal Antibody [Clone ID: 7D3]

Specifications

Product Data
Clone Name	7D3
Applications	ELISA, IF, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human STAT6 expressed in E. Coli.
Specificity	This antibody reacts to STAT6.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	94 kDa
Gene Name	signal transducer and activator of transcription 6
Database Link	Entrez Gene 6778 Human UniProt ID P42226
Background	STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.
Synonyms	IL-4 Stat
Reference Data

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